The study shows the generation of synthetic embryos going through gastrulation and organogenesis in vitro, forming neural folds, a gut and a beating heart. Thanks Gianluca, Charlotte and Magda for the fun collaboration.

This single-cell total RNA-seq method enables complete transcript capture from single-cells at high-throughput. This allowed us to look at splicing an non-coding RNA distribution across mouse gastrulation and organogenesis.

Our preprint with Timo and Anna has been released on biorxiv. We identify Plakoglobin as a mechanosensitive regulator of naive pluripotency, a mechanism that is conserved between mouse and humans, go check it out !

Our preprint with Fredrik Salmen (van Oudenaarden lab, Hubrecht Institute) is out on biorxiv. We develop a new single-cell method that captures most coding and non-coding transcripts across their length (total RNA-seq). The assay can be performed both in plate-based and droplet-based format, this enables the generation of single-cell atlases that contain information on gene regulation and alternative splicing,  go check out the paper!

I finally did it! Now just the graduation and it will be a wrap. Thanks to everyone who made this possible and Florian Hollfelder for hosting me in his laboratory for all these years, very exciting times!

I am delighted to announce I will join the Greg Findlay's group (Genome Function laboratory) for a postodcotral positionat the Francis Crick Institute, where I will employ multiplexed genome editing to study the functional effect of mutations!